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KMID : 0359020070350040254
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Korean Journal of Gastrointestinal Endoscopy
2007 Volume.35 No. 4 p.254 ~ p.257
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A Case of Duodenal GIST Accompanied with Neurofibromatosis-1, Presenting with Gastrointestinal Bleeding
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Seo Sung-O
Oh Hyo-Jeong
Kim Ki-Hoon
Choi Chang-Soo
Seo Geom-Seog
Kim Tae-Hyeon
Yun Ki-Jung
Choi Suck-Chei
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Abstract
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Gastrointestinal stroma tumors (GISTs) are CD117- positive primary mesenchymal tumors of the gastrointestinal tract and are noted to have a possible non-random association with neurofibromatosis-1 (NF-1, Von Recklinghausen disease). We report a case of a duodenal GIST presenting with gastrointestinal bleeding in a 74-year-old female, and this condition was accompanied with NF-1. A upper gastrointestinal endoscopy and abdominal computed tomography scan revealed several submucosal tumors in the duodenum, jejunum and ileum. Histological and immunohistochemical studies on the surgical resection specimen revealed gastrointestinal stromal tumors of an uncommitted type. The patient was treated with local excision of the tumors and is now in a favorable state. (Korean J Gastrointest Endosc 2007;35:254-257)
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KEYWORD
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Gastrointestinal stromal tumor (GIST), Neurofibromatosis-1, Duodenum, Gastrointestinal bleeding
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